Contemporary Management of PE Patients in SHOCK-Who Are We Enrolling in PE Trials?

Who Are We Enrolling in PE Trials?

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Video Summary

The session discussed advancements in clinical trials for acute pulmonary embolism (PE), highlighting various studies and trials. Key trials include PAPO, comparing tenecteplase with anticoagulation, and the FLAME trial on large-bore thrombectomy. Emerging trials like PE-TRACT, STORM-PE, HYPO, PURELESS-2, and PERSEVERE are exploring catheter-based therapies and thrombectomy devices versus anticoagulation for intermediate and high-risk PE patients. These randomized trials aim to assess short-term and long-term outcomes, emphasizing the importance of enrolling diverse patient profiles to comprehensively understand treatment impacts and advance PE management.

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Sameer J. Khandar, MD

Keywords

acute pulmonary embolism

clinical trials

thrombectomy

anticoagulation

catheter-based therapies