SCAI 2026 Bifurcation PCI Reimagined: Data-Driven Decisions in Complex Anatomy-DCB in Bifurcation PCI, Dr. Džavík

Video Transcription

Video Summary

The speaker discussed drug-coated balloons (DCBs) in coronary interventions, especially for in-stent restenosis, small vessels, and bifurcation lesions. He reviewed available DCB types and compared limus- versus paclitaxel-based balloons, noting strong experience in Europe but limited availability in North America. Through several case examples, he showed how IVUS-guided sizing and lesion preparation can reveal undersized stents or calcified bifurcations where DCBs may work well.  <br /><br />He then reviewed evidence suggesting DCBs may reduce major adverse events and target lesion revascularization in bifurcations, but emphasized that the data are sparse, mostly from small or observational studies, and may reflect procedural technique rather than drug effect alone.  <br /><br />The discussion ended with practical guidance: DCBs may be useful in selected bifurcations, especially simple lesions, but better randomized trials are needed. Imaging guidance, good lesion preparation, overnight observation in higher-risk cases, and appropriate antiplatelet/statin therapy were also stressed.

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Keywords

drug-coated balloons

coronary interventions

in-stent restenosis

bifurcation lesions

IVUS-guided sizing

lesion preparation