SCAI 2026 Sirolimus-Eluting Balloons in Coronary PCI: Key Insights from Recent Evidence-Case Review: ISR, Dr. Davies

Video Transcription

Video Summary

The talk reviews in-stent restenosis (ISR), noting its common causes: neointimal hyperplasia, neoatherosclerosis, stent underexpansion, and fracture. It emphasizes that imaging is essential to guide treatment and lesion preparation before using drug-coated balloons (DCBs). Two cases illustrate complex ISR management with combinations of noncompliant balloons, scoring/cutting balloons, intravascular lithotripsy, laser, and repeat imaging to optimize stent expansion, followed by DCB therapy. The speaker concludes that DCBs are an effective, safe alternative to additional stenting when lesions are well prepared, but success depends on careful selection and optimization.

Asset Caption

closed captions are computer-generated

Keywords

in-stent restenosis

neointimal hyperplasia

drug-coated balloons

intravascular imaging

lesion preparation