SCAI 2026 Treatment and Management of Complex Peripheral Arterial Disease-Medical Therapy for Complex PAD, Dr. Monteleone

Medical Therapy for Complex PAD, Dr. Monteleone

Video Transcription

Video Summary

The speaker, an interventional cardiologist, reviews medical management of peripheral artery disease (PAD), emphasizing that PAD signals high cardiovascular risk. He recommends antiplatelet therapy for all PAD patients, usually aspirin or clopidogrel, not both. For selected patients, low-dose rivaroxaban plus aspirin reduces cardiovascular and limb events, especially after revascularization, though bleeding risk rises. He stresses aggressive lipid lowering with statins and possible PCSK9 inhibitors, which also reduce limb events. He briefly mentions symptom relief options, favoring cilostazol over pentoxifylline, and highlights improved diabetes care, including GLP-1 therapies. Overall: treat PAD as a high-risk vascular disease to save lives and limbs.

Asset Caption

closed captions are computer-generated

Keywords

peripheral artery disease

antiplatelet therapy

rivaroxaban aspirin

statins PCSK9 inhibitors

cilostazol