Targeting Inflammation in Atherosclerotic Disease - The New Frontier-The History and Mechanism of Anti-Inflammatory Agents in the Treatment of ASCVD, Dr. Joshua Beckman

The History and Mechanism of Anti-Inflammatory Agents in the Treatment of ASCVD, Dr. Joshua Beckman

Video Transcription

Video Summary

The speaker discusses the historical evolution of using anti-inflammatory therapy in cardiovascular disease, focusing on the role of inflammation and CRP (C-reactive protein) as markers of cardiovascular risk. They highlight key studies showing the impact of inflammation on heart conditions and the benefits of statins in reducing CRP levels. Although past trials, like those involving steroids, were not successful, current research exploring various inflammatory pathways, such as IL-6, and drugs like colchicine, aim to pinpoint effective treatments for atherosclerosis and other related conditions. The speaker emphasizes the importance of identifying which aspects of inflammation contribute to cardiovascular diseases.

Keywords

anti-inflammatory therapy

cardiovascular disease

C-reactive protein

statins

inflammation pathways