Webinar 10 | Assessment of Left Main Stenosis-Cut Off Values for LM, Dr. Duk-Woo Park

Cut Off Values for LM, Dr. Duk-Woo Park

Video Transcription

Video Summary

Dr. Zhu Park discusses the challenge of determining cut-off values for left-main PCI, highlighting discrepancies between Eastern and Western populations. Traditional angiographic diameter stenosis over 50-70% is often used to define significant left-main disease, but visual assessments do not always match physiological measurements like FFR and minimal luminal area (MLA). Contemporary practice favors physiology-guided intervention, particularly using FFR, to identify ischemia-producing lesions that warrant PCI versus those safe for medical therapy. The ongoing "FATE Main" trial aims to validate FFR-guided PCI, emphasizing that careful physiological evaluation can improve patient outcomes by avoiding unnecessary procedures.

Keywords

left-main PCI

fractional flow reserve (FFR)

angiographic diameter stenosis

physiology-guided intervention

FATE Main trial