From Clot Burden to Cardiogenic Shock: IV Antiplatelet Strategies in Acute MI Management
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Description

Intravenous (IV) platelet inhibition has become a crucial aspect of managing high-risk patients undergoing percutaneous coronary interventions (PCI) in the cath lab, particularly for those with acute coronary syndromes (ACS), complex coronary lesions, or high thrombus burden. Expert faculty discuss management of patients with large clot burden, high-risk post-operative complications, the role of IVC P2Y12 inhibitors, and real-world case examples which illustrate the clinical impact of recent data.

Panelists

Binita Shah, MD, FSCAI
Moderator, Case Presentation: Acute MI with Large Clot Burden

Rhian E. Davies, DO, FSCAI
Intraprocedural Management of AMI Patients with Large Clot Burden: From Technique to Pharmacotherapy
Chitra Mosarla, MD
Perioperative Management for Patients at High Risk for Post-Operative Cardiovascular Events: Role of IV P2Y12 Inhibitor
Nathaniel Rosso Smilowitz, MD, FSCAI
Case Presentation: Acute MI with Cardiogenic Shock and Takeaways from Emilsoon OL 2025 Paper
Prashanth D. Thakker, MD, FSCAI
Case Presentation: Non-Cardiac Surgery Patient with High Risk for Post-Operative Cardiovascular Events
   
Learning Objectives
At the end of this activity, participants will be able to:
  1. Analyze the clinical presentation and intraprocedural challenges of acute myocardial infarction (AMI) with large thrombus burden, and evaluate the role of intravenous antiplatelet agents in optimizing reperfusion strategies.
  2. Evaluate the use of intravenous P2Y12 inhibitors in the perioperative management of patients undergoing PCI who are at high risk for post-operative cardiovascular events.
  3. Apply evidence-based strategies to balance ischemic and bleeding risks in the cath lab setting.
  4. Discuss real-world cases presentations involving the use of IV P2Y12 Inhibitor therapy.
Acknowledgement of Commercial Support
This activity is supported by an unrestricted educational grant from Chiesi.
Continuing Education Information

Accreditation Statement
The Society for Cardiovascular Angiography and Interventions (SCAI) is accredited by the 
Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.​

​Credit Designation
SCAI designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.​

​ABIM MOC
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1 medical knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.​

Successful Completion
Watch the content and complete the evaluation to obtain credit.

Activity Timeline
Recording date: 9/23/2026
Publish date: 9/28/2026
Expiration date: 9/28/2029

Copyright
© 2026 Society for Cardiovascular Angiography and InterventionsTM (SCAI). All rights reserved.
Summary
Availability:
On-Demand
Expires on Sep 28, 2029
Cost:
FREE
Credit Offered:
1 CME Credit
1 ABIM-MOC Point
1 Participation Credit
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