Clinical Conversation in Interventional Cardiology: First-in-Human TAVR With Navitor Self-Expanding Intra-Annular Valve in LVAD–Associated Aortic Regurgitation
Program Description

Aortic regurgitation (AR) is a significant complication in patients with left ventricular assist devices (LVADs), leading to poor clinical outcomes due to circulatory inefficiency. Traditional surgical interventions for AR in this population carry high operative risk, and dedicated transcatheter solutions are still under trial and not commercially available.

Join a discussion of the JSCAI manuscript presenting the first-in-human case report on the use of the Abbott Navitor self-expanding intra-annular valve for transcatheter aortic valve replacement (TAVR) in patients with LVAD-associated AR, addressing a critical unmet need in patient care.

Faculty and Program
David G. Rizik, MD, MSCAI
Moderator
Puvi N. Seshiah, MD, FSCAI
Presenting Author
Sachin S. Goel, MD, FSCAI
Panelist
Santiago Garcia, MD, FSCAI
Panelist
Acknowledgement of Commercial Support
This activity is supported by an unrestricted educational grant from Abbott Laboratories.
Learning Objectives
At the end of this activity, participants should be able to:  

Describe the epidemiology and clinical implications of AR in patients with LVADs.
Demonstrate procedural planning and risk management strategies for TAVR in LVAD patients with non-calcified aortic annuli.  
Compare the structural and functional characteristics of the Navitor valve with other TAVR platforms for use in LVAD-associated AR. 
Formulate patient-centered treatment plans for managing severe AR in LVAD patients using off label transcatheter valve therapies.
Accredited Continuing Education Information

Accreditation Statement
The Society for Cardiovascular Angiography and Interventions (SCAI) is accredited by the 
Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

​Credit Designation
SCAI designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

​ABIM MOC
Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn up to 0.5 MOC points in the American Board of Internal Medicine (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABIM MOC credit.

Successful Completion
Watch the content and complete the evaluation to obtain credit.

Activity Timeline
Record Date: 12/4/2025
Publish Date: 3/10/2026
Expiration Date: 3/10/2029

SCAI's Independent Content
As a provider of continuing medical education through the Accreditation Council for Continuing Medical Education (ACCME), it is the Society’s policy to ensure balance, independence, objectivity, and scientific rigor in all its activities.

Planning Process 
SCAI activities are developed by the SCAI Planners prior to and independent of commercial support. Members of the Publications Committee reviewed and approved this activity. If planners had relevant financial relationships, the agenda was peer reviewed by a member with no relevant financial relationships. 

Mitigation of Relevant Financial Relationships
All participating planners, reviewers, faculty, and staff are required to disclose to SCAI any relevant financial relationships. SCAI identifies relevant financial relationships and mitigates them before the activity begins.


Content Validation Statement 

SCAI accepts the following Content Validation Statements and expects all persons involved in its professional education activities to abide by these statements for clinical care recommendations. All clinical and pharmacological recommendations are based on evidence accepted within the medical profession as adequate jurisdiction for their indications and contradictions in patient care. All research referenced to support or justify patient care recommendations conforms to accepted standards of experimental design, data collection and analysis. 

SCAI does not promote recommendations, treatment, or manners of practicing medicine that are not within the definition of accredited continuing education or known to have risks or dangers that outweigh the benefits or known to be ineffective in the treatment of patients. 

SCAI actively promotes improvements in health care and NOT proprietary interests of an ineligible company. 

SCAI's educational content is free of marketing or sales of products or services. Faculty will not actively promote or sell products or services that serve their professional or financial interests during accredited education.  
 
SCAI encourages faculty to identify investigational products or off-label uses of products regulated by the U.S. Food and Drug Administration (FDA), at first mention and where appropriate in the content. 

Copyright
© 2026 Society for Cardiovascular Angiography & Interventions (SCAI). All rights reserved.
Summary
Availability:
On-Demand
Access expires on Mar 10, 2029
Cost:
FREE
Credit Offered:
0.5 CME Credit
0.5 ABIM-MOC Point
0.5 Participation Credit
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