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Clinical Conversation: Novel Mechanical Aspiration Thrombectomy in Patients With Acute Pulmonary Embolism: Results From the Prospective APEX-AV Trial
Program Description

Pulmonary embolism (PE) is the third leading cause of cardiovascular mortality in the U.S., with intermediate-risk PE accounting for 35-55% of hospitalized cases and a mortality rate of 5-24%. Current treatment involves anticoagulation, but adverse outcomes have led to considering more aggressive therapies. The APEX trial and clinical conversation focus on evaluating a new mechanical thrombectomy device for improving patient outcomes.

Faculty and Program
Sahil Parikh, MD, MS
Moderator
Mona Ranade, MD
Presenting Author

William Brent Keeling, MD
Panelist

Kenneth Rosenfield, MD, MSc, MSCAI
Panelist
Acknowledgement of Commercial Support
This activity is supported by an unrestricted educational grant from AngioDynamics
Learning Objectives

At the end of this activity, participants should be able to:

Discuss the clinical significance of acute intermediate-risk PE and the role of mechanical vacuum-assisted thrombectomy in its management
Analyze the clinical efficacy of the AlphaVac F1885 System in patients with acute intermediate-risk PE
Evaluate the safety outcomes associated with percutaneous mechanical aspiration thrombectomy, focusing on the incidence of major adverse events (MAEs) within 48 hours post-procedure

Accredited Continuing Education Information

Accreditation Statement
The Society for Cardiovascular Angiography and Interventions (SCAI) is accredited by the 
Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

​Credit Designation
SCAI designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

​ABIM MOC
Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn up to 0.25 MOC points in the American Board of Internal Medicine (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABIM MOC credit.

Successful Completion
Watch the content and complete the evaluation to obtain credit.

Activity Timeline
Recorded: 2/27/25
Publish date: 4/21/25
Expiration date: 4/21/28

Copyright
© 2025 Society for Cardiovascular Angiography & Interventions (SCAI). All rights reserved.
Summary
Availability: On-Demand
Access expires on Mar 25, 2028
Cost: FREE
Credit Offered:
0.25 CME Credit
0.25 ABIM-MOC Point
0.25 Participation Credit
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