Conversations in Interventional Cardiology - New and Emerging IVL Technologies: Recent Peripheral and Coronary Data from RESTORE ATK and FRACTURE IDE Studies-New and Emerging IVL Technologies: Recent Peripheral and Coronary Data from RESTORE ATK and FRACTURE IDE Studies

New and Emerging IVL Technologies: Recent Peripheral and Coronary Data from RESTORE ATK and FRACTURE IDE Studies

Video Transcription

Video Summary

The webinar reviewed new intravascular lithotripsy (IVL) technologies in peripheral and coronary interventions. Dr. Marian Broadman presented the Restore Above-the-Knee trial of the Seismic IVL system for heavily calcified peripheral artery disease. In 95 patients, the study showed 100% procedural success, no major adverse events through 40 days, very low residual stenosis, and good six-month outcomes. She highlighted improved deliverability and the ability to focus energy at specific vessel sites.<br /><br />Dr. Brian Jefferson then summarized the Fracture IDE trial of the coronary Seismic IVL platform in 420 patients with severe calcified coronary lesions. The study met both safety and efficacy endpoints, with high procedural success, strong stent expansion, and frequent calcium fracture on imaging.<br /><br />The panel discussed how these newer IVL devices may improve deliverability, precision, and treatment of complex calcified disease, while emphasizing the need for comparative data, broader patient inclusion, and future studies in high-risk groups like CKD and nodular calcium.

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Keywords

intravascular lithotripsy

Seismic IVL

calcified lesions

peripheral artery disease

coronary intervention

clinical trial