Endovascular Therapy for Acute PE: SCAI/SIR Update on Ongoing and Completed RCTs-Panel: How Does PEERLESS Affect Our Practice?

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Video Summary

The discussion centers around a study on acute pulmonary embolism treatment, specifically comparing mechanical thrombectomy and catheter-directed thrombolysis (CDT). The trial successfully randomized patients, shedding light on device efficacy and safety. Experts highlight that both devices effectively treat PE, and neither shows superior safety in terms of bleeding and clinical deterioration. However, user experience and patient-specific factors (anatomy, bleeding risks) often dictate treatment choice. There is consensus that although the trial is informative, it hasn't significantly changed existing practice algorithms. The trial confirms that both therapies are effective and relatively safe, encouraging flexibility in choosing treatment strategies. Additionally, new algorithms and trials exploring on-table thrombolysis might influence future practice. The discussion emphasizes ongoing evolution in PE treatment, underscoring the importance of further research to refine and improve therapeutic approaches.

Keywords

acute pulmonary embolism

mechanical thrombectomy

catheter-directed thrombolysis

treatment algorithms

therapeutic approaches